Vanderbilt University Research Assistant I (Meiler Lab/Chemistry) in Nashville, Tennessee

Research Assistant I (Meiler Lab/Chemistry) (Job Number: 1800377)


About the Position: A Research Assistant I position is open to provide support to the Meiler Lab. The role will perform administrative, research and technical duties of the laboratory. Primary responsibility will be production of recombinant proteins for study by NMR, X-ray Crystallography and a variety of biophysical methods. The individual will work closely with graduate students, postdoctoral fellows and laboratory manager in a dynamic laboratory environment. The ability to function independently as well as part of a team is critical. Excellent organizational and communications skills (both verbal and written) are essential, as is attention to detail.

About the Department: Research in the Meiler laboratory seeks to fuse computational and experimental efforts to investigate proteins, the fundamental molecules of biology, and their interactions with small molecule substrates, therapeutics, or probes. We develop computational methods with three major ambitions in mind:

  • To enable protein structure elucidation of membrane proteins theprimary target of most therapeutics and large macromolecular complexes such asviruses;

  • Designproteins with novel structure and/or function to explore novel approaches toprotein therapeutics and deepen our understanding of protein folding pathways.

  • Understandthe relation between chemical structure and biological activity quantitativelyin order to design more efficient and more specific drugs.

Learn more about the Meiler Lab here:

About Vanderbilt: Vanderbilt is a renowned private institution founded in 1873 located a little more than a mile from downtown Nashville, TN. The university’s students, faculty, staff and visitors frequently cite Nashville as one of the perks of Vanderbilt. VU is a place where your expertise will be valued, your knowledge expanded and your abilities challenged. It is a place where your diversity is sought and celebrated. It is a place where employees know they are part of something that is bigger than themselves, take exceptional pride in their work and never settle for what was good enough yesterday.

Key Functions and Expected Performances:

Assist in Research and Development

  • Preparation of buffers and reagents

  • Production of vectors for protein expression

  • Bacterial overexpression of protein

  • Protein purification

  • Writing and updating laboratory protocols as needed

  • Perform, interpret and evaluate research

  • Perform test experiment procedures relating to laboratoryactivities

  • Assemble and compile research data for presentation and/orpublication

  • Assist in collaborative efforts with other institutions and/orindustry

  • Maintenance of laboratory equipment

  • Shipment of purified proteins to collaborators

  • Proper storage and maintenance of protein stocks

  • Participate in weekly and bimonthly meetings to discussproject progress

  • Other tasks as directed by supervisor

Ensure the most effective operation of the laboratory

  • Maintain procedures manual

  • Maintain chemical inventory

  • Maintain an inventory of supplies

  • Anticipate the laboratory needs and order supplies for on-goingand future experiments

  • Negotiate pricing for sales and service of equipment, supplies,and contracts

Website maintenance

  • Update laboratory program website using existing platforms

  • Ensure website contains current information

Perform administrative duties

  • Prepare lab calendar

  • Respond to requests of students, postdoctoral fellows and faculty

  • Update list of seminars as announced

  • Reservations of various meeting rooms

  • Coordinate guest visits including itineraries

  • Flexibility to complete non-routine assignments

  • Assist laboratory manager in administrative aspects of the RosettaWorkshop

Qualifications: Bachelor's degree in biochemistry, biological sciences, or related field and a minimum of 2 years of experience in a research setting, the latter can be substituted with a Master’s degree.

Preferred Education, Skills, andExperiences:

  • Degree in Chemistry or other related science field

  • Experience working in a research lab

  • Experience working with students and faculty

  • Experience in E. coli transformation, protein expression andbacterial cell culture is preferred

  • Experience in purification of proteins by both bench top andautomated chromatographic methods is desired

  • Experience in flow cytometry

  • Molecular biology experience is preferred

  • Effective communicator

This is a full-time position; 40 hours per week; Monday - Friday.

Salary is dependent upon education and experience.

Benefits: In addition to offering a lively community that encourages learning and celebrates diversity, VU offers a competitive, flexible benefits package including health, dental, vision, life, accidental death & dismemberment, disability insurance, paid time off, and a 403(b) retirement plan with employer match. Vanderbilt offers tuition assistance to employees, spouses and dependent children. Also, after five years of service, Vanderbilt will pay up to 55% of the tuition for up to three dependent children to earn a bachelor's degree. Learn more about Vanderbilt's benefits at VU Benefits Overview at

This position requires a Bachelors degree and 2 Years of experience or the equivalent.

Primary Location: United States-Tennessee-Nashville

Organization: 12520 - Chemistry

Job: Research / Lab Tech / Paraprofessional