Vanderbilt University Staff Scientist in Nashville, Tennessee

Staff Scientist (Job Number: 1801641)


Position Summary :

The Staff Scientist conducts research into the ability of endogenous electrophiles to damage genetic material and alter epigenetic programming. A major aspect of the research will be to develop and apply specific and sensitive analytical methods to quantify the extent of damage to DNA and protein that occurs as a result normal metabolism or metabolism associated with acute and/or chronic inflammation. Genetic material will be isolated from the nucleus and mitochondria of intact cells or intact tissues (animal or human) and analyzed for the presence of adducts formed by endogenous electrophiles. The principal analytical method that will be used for this research is liquid chromatography/tandem mass spectrometry. The Staff Scientist will have skills in modern mass spectrometry as well as cell culture. The position will conduct research independently; this means planning and executing experiments with occasional input from the supervisor. The position will be responsible for drafting progress reports, grant applications and manuscripts describing the results of the research. The position will also work with undergraduates doing projects in the laboratory.

About the Work Unit :

The laboratory studies the role of inflammation in human disease, particularly cancer. It is comprised of five individuals employed full- or part-time and uses a range of chemical, biochemical and biological concepts and technologies. The staff scientists or research track faculty in the laboratory serve as a core for conducting research and interact with postdoctoral fellows or undergraduates who occasionally join the laboratory. Individuals in the laboratory engage in a high degree of collaboration when working on projects.

Key Functions and Expected Performance:

Conduct independent research:

  • Designs and executes experiments with minimal supervision from the PI

  • Interprets data and uses results to design the next set of experiments

  • Develops skill in the use of liquid chromatography/tandem mass spectrometry and cell culture

  • Conducts animal experiments

Transcribe progress reports and manuscript drafts:

  • Analyzes data to communicate results and implications in a clear fashion

  • Drafts animal protocols for submission to IACUC

Participate with team members and train undergraduates:

  • Supervises, monitors, and trains undergraduates completing immersion projects

  • Works as part of a team to share results and plan complex experiments

Supervisory Relationships :

This position may supervise and train undergraduates; the position reports administratively and functionally to the Principal Investigator.

Education and Certifications:

  • A PhD from an accredited institution of higher education in Biochemistry is necessary.

Experience and Skills :

  • At least three years of postdoctoral training is necessary.

  • Experience working with working with undergraduates is necessary.

  • Experience in cell culture and protein/DNA isolation is necessary.

  • Comprehensive knowledge and experience in mass spectrometry is necessary.

  • Experience in a range of routine biochemical and physiological techniques is necessary.

  • Ability to develop scientific reports and manuscripts based on original research is necessary.

  • Ability to design, organize, and coordinate scientific and/or engineering research projects is necessary.

  • Knowledge of scientific approach and methodologies is preferred.

  • Skill in organizing resources and establishing priorities is preferred.

  • Ability to use independent judgment to develop model concepts and approaches for research is preferred.

  • Ability to plan, develop, and manage highly influential and/or groundbreaking research projects in area of expertise is preferred.

  • Ability to utilize advanced computer statistical and technical applications is preferred.

Key Characteristics of a Successful Team Member in this Work Unit:

  • Teamwork – Genuinely values teamwork and co-workers; make them feel valuable and important by acknowledging what they do well. Doesn’t expect from others effort that one is unwilling to do themselves. Finds ways to acknowledge other’s strong suits.

  • Autonomous – Self-managing; self-motivated. Manages time, activities and outcomes well so that progress stays on track. Cleans up after themselves.

  • Reliable – Does what they say they will do, when they say they will do it. Shows up for work when expected. Doesn’t push the burden of work volume or deadlines to others.

  • Analytical & Detail-Oriented – Accurately assesses information and applies applicable law, policy and procedure. Considers the long term implications of actions today and advises employees appropriately. Even small mistakes can create big issues; attention to detail work indicates care about the outcomes.

  • Maturity – Exhibits professional maturity; doesn’t pass the buck to dodge accountability; doesn’t engage in petty office politics or inappropriate social conduct.

Job requires Doctorate and 2 Years of experience or the equivalent.

Primary Location: United States-Tennessee-Nashville

Organization: 18220 - Biochemistry

Job: Research, Extension, and Other Education Professionals

Vanderbilt University is committed to principles of equal opportunity and affirmative action